Immunopathogenesis of Chronic Rhinosinusitis and Nasal Polyposis
نویسندگان
چکیده
منابع مشابه
Current concepts in therapy of chronic rhinosinusitis and nasal polyposis.
The exact pathophysiological mechanisms leading to chronic rhinosinusitis (CRS) still to a large extent remain obscure. However, recently there has been some progress in elucidating the etiology of nasal polyposis, especially regarding tissue eosinophilia as well as the role of aspirin intolerance and eicosanoid mediators. Endonasal sinus surgery has evolved to be the treatment of choice in CRS...
متن کاملSystemic corticosteroids for allergic fungal rhinosinusitis and chronic rhinosinusitis with nasal polyposis: a comparative study.
OBJECTIVES To compare the effect of preoperative high-dose systemic corticosteroids on the radiographic and endoscopic appearance of allergic fungal rhinosinusitis (AFRS) and chronic rhinosinusitis with nasal polyposis (CRSwNP). STUDY DESIGN AND SETTING Eight AFRS and 10 CRSwNP patients underwent computed tomographic (CT) scans and then received preoperative 1 mg/kg prednisone for 10 days. CT...
متن کاملSerum 25-Hydroxy Vitamin D in Chronic Rhinosinusitis with and Without Nasal Polyposis: A Case-Control Study in Northern Iran
Introduction: Chronic rhinosinusitis (CRS) with and without nasal polyposis is a chronic inflammatory disease of the sinuses and nasal mucosa. Recent evidence has indicated a relationship between serum 25-hydroxyl vitamin D (OH-VitD) deficiency and CRS. Regarding this, the present study aimed to compare the serum level of 25-OH-VitD in CRS patients with and without nasal polyposis and control g...
متن کاملChange in nasal congestion index after treatment in patients with chronic rhinosinusitis with nasal polyposis
BACKGROUND The management of chronic rhinosinusitis with nasal polyposis (CRSwNP) involves both surgical and medical approaches, and remains a controversial subject. OBJECTIVE The objective of this prospective, randomized, controlled trial was to compare the medical and surgical treatments of CRSwNP in terms of their effect on the nasal congestion index (NCI). METHODS Forty-eight patients w...
متن کاملThe impact of chronic rhinosinusitis and nasal polyposis in quality of life.
Multiple studies indicated that chronic rhinosinusitis is associated with a dramatic reduction in patient quality of life. The presence of asthma and atopy may have cumulative and negative impact on quality of life. To assess quality of life, specific and generic questionnaires may be used. Specific questionnaires are usually focused on one particular area such as a disease state, a selected po...
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ژورنال
عنوان ژورنال: Annual Review of Pathology: Mechanisms of Disease
سال: 2017
ISSN: 1553-4006,1553-4014
DOI: 10.1146/annurev-pathol-052016-100401